BDBM25136 2-cyano-pyrropyrimidine, 7b::7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl)-3-fluorophenoxymethyl]-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile

SMILES CC(=O)N1CCN(CC1)c1ccc(OCc2cc3cnc(nc3n2CCC2CCCCC2)C#N)cc1F

InChI Key InChIKey=ACIMELNVMJNHRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25136   

TargetProcathepsin L(Homo sapiens (Human))
Novartis

LigandPNGBDBM25136(2-cyano-pyrropyrimidine, 7b | 7-(2-cyclohexylethyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed